Adenosine and KOH processing

Chemistry and homework help forum.

Organic Chemistry, Analytical Chemistry, Biochemistry, Physical Chemistry, Computational Chemistry, Theoretical Chemistry, High School Chemistry, Colledge Chemistry and University Chemistry Forum.

Share your chemistry ideas, discuss chemical problems, ask for help with scientific chemistry questions, inspire others by your chemistry vision!

Please feel free to start a scientific chemistry discussion here!

Discuss chemistry homework problems with experts!

Ask for help with chemical questions and help others with your chemistry knowledge!

Moderators: Xen, expert, ChenBeier

Post Reply
BooMeR
Newbie
Newbie
Posts: 1
Joined: Tue Jul 07, 2009 8:51 am

Adenosine and KOH processing

Post by BooMeR »

Adenosine -C10H13N5O4
(9-β-D-Ribofuranosyladenine, Adenine riboside, Adenine-9-β-D-ribofuranoside)

Need to reduce the endotoxin (lipopolysaccharides found in the outer membranes of gram negative bacteria) level in Adenosine. Although I have found that dissolving ~2.0g in 16ml of 5N KOH for 4 hours reduces/eliminates the endotoxins, I need to know if dissolving in the KOH is changing or breaking down the Adenosine? Will it break it down into Adenine and Ribose?

Before experimenting with the KOH concentration needed and the amount of time required before neutralizing the solution, I want to assure that I will still have Adenosine after treatment (and at the required levels).

http://en.wikipedia.org/wiki/Adenosine
Post Reply