LOQ/LOD Calculations (ICP-MS)

Chemistry and homework help forum.

Organic Chemistry, Analytical Chemistry, Biochemistry, Physical Chemistry, Computational Chemistry, Theoretical Chemistry, High School Chemistry, Colledge Chemistry and University Chemistry Forum.

Share your chemistry ideas, discuss chemical problems, ask for help with scientific chemistry questions, inspire others by your chemistry vision!

Please feel free to start a scientific chemistry discussion here!

Discuss chemistry homework problems with experts!

Ask for help with chemical questions and help others with your chemistry knowledge!

Moderators: Xen, expert, ChenBeier

Post Reply
Posts: 1
Joined: Thu Jul 28, 2022 5:18 am

LOQ/LOD Calculations (ICP-MS)

Post by Kupy »

Good afternoon everyone,

I work in a company where we do analysis of medical material elements with ICP-MS. At the time the LOD and LOQ were calculated with the following formula.


- C1 = concentration of the high sample
- C0 = concentration of the blank
- I1 = raw intensity of the high sample (cps)
- I0 = raw intensity of the blank (cps)

I had always used a simpler formula, although it is similar. The problem is that I can't find too many references to this formula and I don't know if it appears in any Guideline.

Could someone help me?

Thank you very much!
Post Reply