Methylation C 2 Position imidazolium

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Joined: Tue Jan 11, 2022 2:02 pm

Methylation C 2 Position imidazolium

Post by Iceeverdeen »

Hi there,

has anyone an idea how to successfully methylate the C2 position of an imidazolium?
Tried myself the bases n-BuLi, KotBu, KHMDS and NaH with MeI as methylation agent-with either oxidation problems or minor species.
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